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Inter Milan followed up their passage into the Champions League final with a 2-0 defeat of Lazio on Sunday as Jose Mourinho's side edged closer to a fifth successive Serie A title.

With just two games left, Inter restored their two-point lead over Roma, who won 2-1 at Parma on Saturday, and also stayed on course for a treble.

They face Roma in the Italian Cup final on Wednesday and Bayern Munich in Madrid on May 22 in the Champions League final.

Inter face lowly opposition in their last two league games - Chievo (12th place) at home next weekend before a trip to relegated Siena (19th).

Roma also face Chievo a week after welcoming 14th-placed Cagliari.

But Roma could have a 'joker' to play because if the two sides are level on points at the end of the season, the capital city side would be champions thanks to their better head-to-head record against Inter.

A 1-1 draw in Milan was followed by a 2-1 home win at the Olympic Stadium.

On Sunday, Lazio fans, with their team languishing two places off the relegation zone, but reluctant to see their Roma rivals take the championship, were content to see Argentine defender Walter Samuel head in the first goal on the stroke of half-time from a Wesley Sneijder cross.

Inter, fresh from knocking defending champions Barcelona out of the Champions League in midweek, piled on the pressure, but found Lazio goalkeeper Fernando Muslera in inspired form.

Muslera saved well from Maicon, Thiago Motta, Sneijder and Samuel Eto'o in the first half.

But the home side's resistance crumbled in the 70th minute when Motta scored from a Maicon corner.

Earlier, Sampdoria and Palermo remained locked in battle for fourth place and the final Champions League qualifying spot after both recorded wins.

Sampdoria, who lead Palermo by two points, at times laboured to a 2-0 success at home to rock-bottom and already relegated Livorno while the Sicilians held on to a 2-1 victory at Siena.

Antonio Cassano scored the only goal of the game after just five minutes as he got beyond the defence and beat goalkeeper Alfonso De Lucia.

Cassano should have given Sampdoria breathing space six minutes before the break but somehow contrived to fire wide from a great position.

Cassano was having one of his champagne days on the pitch and twice set up Giampaolo Pazzini but he couldn't finish.

However, six minutes from time Swiss full-back Reto Ziegler crashed home a free-kick to calm Sampdoria nerves.

They stay fourth, four points behind AC Milan.

Siena joined Livorno in Serie B next season after their relegation was confirmed by the defeat to Palermo.

Uruguayan forward Edison Cavani gave the visitors the lead on 24 minutes after converting a cross from Antonio Nocerino.

When Fabrizio Miccoli added the second just before the hour mark, the game seemed over but 10 minutes from time Emanuele Calaio headed home a cross from former Middlesbrough forward Massimo Maccarone to set up a tense finish.

In other games Napoli and Juventus both ensured themselves a place in the Europa League next season.

Napoli won 2-1 away to Chievo thanks to goals from Argentine pair German Dennis and Ezequiel Lavezzi, sandwiching a Pablo Granoche strike.

Juventus dropped to seventh, a point behind Napoli, but secured their spot with a 1-1 draw at Catania due to Genoa's 3-0 defeat at Bari.

Bologna boosted their survival hopes as they came back from a goal down to draw 1-1 at 10-man Atalanta.